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Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair

机译：EDO-s101的临床前抗骨髓瘤活性，一种新的苯达莫司汀衍生的分子，具有增加的HDaCi活性，通过有效的DNa损伤诱导和DNa修复损伤

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Ana-Alicia López-Iglesias; Ana B. Herrero; Marta Chesi; Laura San-Segundo; Lorena González-Méndez; Susana Hernández-García; Irena Misiewicz-Krzeminska; Dalia Quwaider; Montserrat Martín-Sánchez; Daniel Primo; Teresa Paíno; P. Leif Bergsagel; Thomas Mehrling; Marcos González-Díaz; Jesús F. San-Miguel; María-Victoria Mateos; Norma C. Gutiérrez; Mercedes Garayoa; Enrique M. Ocio;
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1. Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair [J] . Ana-Alicia López-Iglesias, Ana B. Herrero, Marta Chesi, Journal of Hematology and Oncology . 2017,第1期

机译：EDO-S101的临床前抗骨髓瘤活性是一种新的由苯达莫司汀衍生的分子，具有增强的HDACi活性，通过有效的DNA损伤诱导和DNA修复受损
2. Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair [J] . Ana-Alicia López-Iglesias, Ana B. Herrero, Marta Chesi, Journal of Hematology and Oncology . 2017,第1期

机译：EDO-S101的临床前抗骨髓瘤活性是一种新的由苯达莫司汀衍生的分子，具有增强的HDACi活性，通过有效的DNA损伤诱导和DNA修复受损
3. Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus [J] . Lim Carine S. Q., Ha Kam Pou, Clarke Rebecca S., Bioorganic and medicinal chemistry . 2019,第20期

机译：鉴定有效的小分子抑制细菌DNA修复抑制剂，其增强了喹啉抗生素AUREUS中的喹诺酮抗生素活性
4. Structural and Biophysical Investigations of a New Family of Transfection Peptides with Potent siRNA and DNA Delivery Activities [C] . Burkhard Bechinger, Antoine Kichler Japanese peptide symposium . 2011

机译：具有效率siRNA和DNA递送活性的新型转染肽的结构和生物物理研究
5. Potent 3-methylindole-mediated DNA damage, cytochrome p450 induction, and mutagenicity in human lung. [D] . Weems, Jessica Marie. 2010

机译：3-甲基吲哚介导的强力DNA损伤，细胞色素p450诱导和人肺致突变性。
6. Preclinical anti-myeloma activity of EDO-S101 a new bendamustine-derived molecule with added HDACi activity through potent DNA damage induction and impairment of DNA repair [O] . Ana-Alicia López-Iglesias, Ana B. Herrero, Marta Chesi, 2017

机译：EDO-S101的临床前抗骨髓瘤活性是一种由苯达莫司汀衍生的新分子具有强大的HDACi活性通过有效的DNA损伤诱导和DNA修复受损
7. Interaction of antimutagenic 1,4-dihydropyridine AV-153-Na with DNA and DNA-damaging molecules and its impact on DNA repair activity [O] . Elina Leonova, Evita Rostoka, Sylvie Sauvaigo, 2017

机译：抗型1,4-二氢吡啶AV-153-NA与DNA和DNA损伤分子的相互作用及其对DNA修复活性的影响

Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair

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